Simple install: % perl Makefile.PL MP_APXS=/usr/local/apache2/bin/apxs % make && make test % make install If Apache was built but not installed yet or if apxs is not available and Apache was installed under a single tree (e.g., /usr/local/apache2), you should use the MP_AP_PREFIX option, which points that the Apache tree: % perl Makefile.PL MP_AP_PREFIX=/usr/local/apache2 See docs/user/install/install.pod for details. Simple config: LoadModule perl_module modules/mod_perl.so If the MP_INST_APACHE2=1 option was given to Makefile.PL, you'll want to configure: PerlModule Apache2 For compat with the 1.x version, you'll want to configure: PerlModule Apache::compat See docs/user/config/config.pod for details.